Case Report
Pulmonary Nocardiosis in the Immunocompetent Host: Case Series
Table 1
Antimicrobial susceptibilities of Nocardia species isolated from sputum cultures.
| | Antibiotic | Nocardia cyriacigeorgica | Nocardia nova | | Case MIC | Case 2 MIC | Case 3 MIC | Case 4 MIC | | (μg/mL) | (μg/mL) | (μg/mL) | (μg/mL) |
| | Amikacin | ≤8 S | ≤1 | ≤1 S | ≤8 S | | Amoxicillin/Clavulanate | 16/8 Int. | 32/16 R | 4/2 S | >32/16 R | | Azithromycin | 64 Int. | Not available | Not available | ≤16 S | | Cefepime | 8 S | Not available | Not available | ≤4 S | | Cefotaxime | ≤8 S | Not available | Not available | ≤8 S | | Ceftriaxone | ≤8 S | 8 S | ≤4 | ≤8 S | | Ciprofloxacin | >8 R | 4 R | >4 R | >8 R | | Clarithromycin | 8 Int. | >16 R | 8 R | ≤25 R | | Clofazimine | ≤0.5 S | Not available | Not available | 0.5 S | | Doxycycline | Not available | 4 Int. | 8 R | Not available | | Gentamicin | ≤2 S | Not available | Not available | 16 R | | Imipenem | ≤2 S | 4 S | ≤2 S | ≤2 S | | Kanamycin | 16 R | Not available | Not available | 16 R | | Linezolid | 2 S | 2 S | 2 S | ≤1 S | | Minocycline | ≤1 S | 2 Int. | >8 R | 4 S | | Moxifloxacin | Not available | 4 R | 4 R | Not available | | Tobramycin | ≤2 S | ≤1 S | ≤1 S | >16 R | | Trimethoprim/Sulfamethoxazole | ≤0.5/9.5 S | ≤0.25/4.8 S | 0.5/9.5 S | 2/38 S |
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MIC: minimum inhibitory concentration; S: sensitive; R: resistant; Int: intermediate.
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