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Case Reports in Pulmonology
Volume 2016 (2016), Article ID 2020146, 4 pages
http://dx.doi.org/10.1155/2016/2020146
Case Report

Key Features in the Management of Pulmonary Carcinosarcoma

1Department of Cardiothoracic Surgery, University College London Hospitals (UCLH), 16-18 Westmoreland Street, London W1G 8PH, UK
2Department of Pathology, University College London Hospitals (UCLH), 21 University Street, Rockefeller Building, London WC1E 6DE, UK

Received 20 October 2015; Accepted 26 January 2016

Academic Editor: Daniel T. Merrick

Copyright © 2016 Nikolaos Panagiotopoulos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Pulmonary carcinosarcoma represents a category of extremely rare tumours accounting for 0.1% of all lung malignancies. It is defined as a poorly differentiated non-small-cell carcinoma that contains a component of sarcoma or sarcoma-like elements. These biphasic tumours typically have a poor prognosis due to late diagnosis and early metastases. Preoperative tissue diagnosis is usually difficult due to the heterogeneity of the tumour, with biopsies often just reflecting one element of the tumour. By means of a case illustration and review of the literature, we discuss the optimal management of patients with pulmonary carcinosarcoma.