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Case Reports in Radiology
Volume 2011, Article ID 371073, 4 pages
http://dx.doi.org/10.1155/2011/371073
Case Report

1 H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?

1Department of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UK
2Department of Neurosurgery, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UK

Received 6 June 2011; Accepted 13 July 2011

Academic Editor: M. Fujioka

Copyright © 2011 M. Szewczyk-Bieda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.