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Case Reports in Radiology
Volume 2015, Article ID 241259, 7 pages
Case Report

Malignant Peripheral Nerve Sheath Tumor: MRI and CT Findings

Department of Radiology, University of Louisville, 530 S. S. Jackson Street, CCB C07, Louisville, KY 40202, USA

Received 28 April 2015; Revised 24 September 2015; Accepted 7 October 2015

Academic Editor: Salah D. Qanadli

Copyright © 2015 K. O. Kragha. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology biopsy result showed malignant peripheral nerve sheath tumor (MPNST) with extensive necrosis. The diagnosis of MPNST is extremely difficult due to the lack of (1) conclusive immunohistochemistry or unique chromosomal anomaly, (2) universal distinctive histopathology, and (3) clinical criteria. The clinical, radiologic, and histologic presentation of MPNST is important in its diagnosis. A rare case of MPNST that produced urinary retention and bowel incontinence is presented that may aid clinicians in the diagnosis of this rare clinical entity. Motor weakness, central enhancement, and immunohistochemistry may assist in the diagnosis of MPNST and differentiation between benign peripheral nerve sheath tumor (BPNST) and MPNST.