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Case Reports in Radiology
Volume 2015, Article ID 727510, 4 pages
Case Report

Radiographic and MR Imaging Findings of the Spine after Bisphosphonate Treatment, in a Child with Idiopathic Juvenile Osteoporosis

12nd Department of Radiology, “Attikon” University Hospital, National and Kapodistrian University of Athens, Rimini 1, Chaidari, 124 62 Athens, Greece
23rd Department of Pediatrics, “Attikon” University Hospital, Chaidari, 124 62 Athens, Greece

Received 9 August 2014; Revised 10 November 2014; Accepted 4 December 2014

Academic Editor: Atsushi Komemushi

Copyright © 2015 Olympia Papakonstantinou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Bisphosphonates are employed with increasing frequency in various pediatric disorders, mainly associated with osteoporosis. After cessation of bisphosphonate treatment in children, skeletal radiologic changes have been documented including dense metaphyseal lines of the long bones and “bone in bone” appearance of the vertebrae. However, the evolution of these radiographic changes has not been fully explored. We describe the MR imaging appearance of the spine that, to our knowledge, has not been previously addressed in a child with idiopathic juvenile osteoporosis who had received bisphosphonates and emphasize the evolution of the radiographic findings of the spine and pelvis over a four-year period.