Parotid Oncocytoma as a Manifestation of Birt-Hogg-Dubé Syndrome

Table 1

Reported cases of parotid oncocytoma in Birt-Hogg-Dubé syndrome.

Case	Year	First author; and region	Age at diagnosis, years; /Sex	Mutation	Pathology of parotid tumor (Age at diagnosis)	Skin	Lung; (Age, years)	Kidney; (Age, years)	Family history
1	2000	Liu et al. [5]; North America	56/M	N/A	Oncocytoma (55)	FF	PTX,; LC	-	Sister (PTX, LC)
2-4	2005	Schmidt et al [6]; North America	N/A	N/A	Oncocytoma	N/A	N/A	N/A	N/A
5	2011	Maffé et al. [7]; Europe	53/M	c.347 dup A; (exon 5)	Oncocytoma; (32, right; 43, left)	FF; or; TD	PTX; (42)	CCC; (37)	Father (hybrid CCC/on with CCC component accounting for 60% of the lesion and sigmoid adenocarcinoma)
6	2012	Lindor et al. [8]; North America	45/F	c.779+1 G>T; (exon 7i)	Oncocytic neoplasm (45)	FF	-	-	Maternal grandfather (prostate cancer), maternal grandmother (bladder cancer, lung cancer)
7	2013	Pradella et al. [9]; Europe	N/A	c.347 dupA; (exon 5)	Oncocytoma	FF	PTX; LC	N/A	N/A
8	2016	Present report; Yoshida et al.; Asia	45/F	c.1285dupC; (exon 11)	Clear cell; oncocytoma (44)	-	PTX (45); LC	-	Father (PTX); Brother (PTX)

M: male: F: female; FF: fibrofolliculoma; TD: trichodiscomas; PTX: pneumothorax; LC: lung cysts; CCC: clear cell carcinoma; N/A: not available.