A Case Series of Breast Metastases from Different Extramammary Malignancies and Their Literature Review

Figure 10

Case 10. A 63-year-old man with gastric signet ring cell carcinoma. One month after diagnosis, the patient presented with a palpable mass in the left breast (b and d). Mammogram showed focal asymmetry in the retroareolar region in the left breast and a high-density mass that resulted in nipple retraction (a–d). On ultrasound, this corresponded to a suspicious, solid heterogeneous mass with indistinct margins and posterior acoustic shadowing (e–f). A comparable lesion was demonstrated in the right breast. HE staining and immunohistochemistry analysis of the metastases. HE staining revealed the malignant cells in the breast tumor (g), and the immunohistochemistry analysis indicated that the cells were positive for PAS (h) and Alcian blue (i).

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