A Case Series of Breast Metastases from Different Extramammary Malignancies and Their Literature Review

Figure 3

Case 3. A 41-year-old woman diagnosed with a low-differentiated carcinoma. Contrast-enhanced computed tomography (CT) scan demonstrated an incidental finding consistent with a mass on the right breast (a). Although this lesion was palpable, it was not detectable on mammography (b). Then, an ultrasound was performed, showing an oval mass with parallel orientation, indistinct margins, a heterogeneous echo pattern, and posterior acoustic enhancement (c–d). HE staining and immunohistochemistry analysis of the metastases. HE staining revealed the malignant cells in the breast tumor (e), and the immunohistochemistry analysis indicated that the cells were positive for PAX8 (f) and WT4 (g).

(a)

(b)

(c)

(d)

(e)

(f)

(g)