A Case Series of Breast Metastases from Different Extramammary Malignancies and Their Literature Review

Figure 4

Case 4. A 56-year-old woman diagnosed with ovarian adenocarcinoma. One month after diagnosis, the patient presented with palpable axillary adenopathy. Mammogram showed dermal and trabecular thickening in the left breast, with diffusely increased density of the mammary tissue (a–b). On ultrasound, an irregular hypoechoic mass with indistinct margins was revealed (c). An axillary lymph node with cortical indentation was also observed by ultrasound (d). HE staining and immunohistochemistry analysis of the metastases. HE staining revealed the malignant cells in the breast tumor (e), and the immunohistochemistry analysis indicated that the cells were positive for PAX8 (f).

(a)

(b)

(c)

(d)

(e)

(f)