Leukocytoclastic Vasculitis in a Patient with Type 1 Cryoglobulinemia

Figure 1

(a) Leukocytoclastic vasculitis of thin walled, papillary dermal vessels characterized by mural fibrinoid necrosis and nuclear dust (arrow). A marked perivascular neutrophilic infiltrate and many extravasated red blood cells are present (hematoxylin and eosin stain; 100×). (b) Intraluminal monoclonal immunoglobulin casts in superficial papillary dermal vessels. Note swollen endothelial cells (arrow) (periodic acid-schiff stain, 400×).

(a)

(b)