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Case Reports in Rheumatology
Volume 2012 (2012), Article ID 515768, 3 pages
http://dx.doi.org/10.1155/2012/515768
Case Report

Transverse Myelitis Associated with Anti-Ro (SSA) Autoantibodies: A Record of Two Cases

1Neurology Section, Department of Medicine, Hamad General Hospital, P.O. Box 3050, Doha, Qatar
2Rheumatology Section, Department of Medicine, Hamad General Hospital, P.O. Box 3050, Doha, Qatar
3General Medicine Section, Department of Medicine, Hamad General Hospital, P.O. Box 3050, Doha, Qatar

Received 22 September 2012; Accepted 9 October 2012

Academic Editors: R. Aminov, J. Mikdashi, P. Njobvu, and T. K. Tso

Copyright © 2012 G. Melikyan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype and autoantibody provides circumstantial evidence that an autoimmune aetiology might be involved. We describe two cases of TM associated with anti-Ro (SSA) autoantibodies without connective tissue disease manifestations. The two patients were treated successfully with IV steroids and cyclophosphamide.