Case Reports in Rheumatology / 2015 / Article / Fig 3

Case Report

A Case of Immunoglobulin G4-Related Disease with Extensive Multiorgan Involvements

Figure 3

Histopathological findings of the specimen obtained by needle renal biopsy. IgG4 staining (a, b, c) revealed infiltration of numerous IgG4-positive cells and absence of normal structure in some parts of the interstitium and almost-normal structures with only slightly edematous interstitium in other parts. The IgG4/IgG ratio of infiltrating plasma cells was over 90%. Formation of crescents and mesangium cell proliferation were not evident in glomeruli in HE staining (d).

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