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Case Reports in Rheumatology
Volume 2015, Article ID 721078, 2 pages
http://dx.doi.org/10.1155/2015/721078
Case Report

Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner

1Clinical Investigation Center for Biotherapy, CIC-1431, FHU INCREASE, University Hospital of Besançon, 25000 Besançon, France
2Department of Rheumatology, University Hospital of Besançon, 25000 Besançon, France
3Department of Therapeutics and EA 4266 “Pathogens and Inflammation”, SFR FED 4234, University of Franche-Comté, 25000 Besançon, France
4Department of Sport Medicine, University Hospital of Besançon, 25000 Besançon, France
5Department of Cardiology, University Hospital of Besançon, 25000 Besançon, France
6EA3920 “Marqueurs Pronostiques et Facteurs de Régulation des Pathologies Cardiaques et Vasculaires” SFR FED 4234, University of Franche-Comté, 25000 Besançon, France

Received 8 October 2014; Accepted 17 February 2015

Academic Editor: George S. Habib

Copyright © 2015 Éric Toussirot et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Statins are widely used in the treatment of hypercholesterolemia and their side effects on muscles are well established. Conversely, data are sparse regarding the safety of this class of drugs in subjects who engage in sports, particularly those who have intense sports activity. We report the case of a marathon runner who presented with acute rhabdomyolysis during competition while being under rosuvastatin treatment. This case raises the question of the need for temporary discontinuation of statin therapy when intense physical activity is planned.