Case Report

Three Cases of Previous Smokers with Rheumatoid Arthritis Who Did Not Respond to Tumor Necrosis Factor Inhibitors Were Treated Successfully with an Anti-Interleukin-6 Receptor Antibody

Figure 2

Summary of the clinical course of case 2. DAS28-CRP Disease Activity Score assessing 28 joints with C-reactive protein. BU: bucillamine, PSL: prednisolone, GST: gold sodium thiomalate, MTX: methotrexate, MZR: mizoribine, ETN: etanercept, ADA: adalimumab, TCZ: tocilizumab, and MMP-3: matrix metalloproteinase-3. The asterisk shows the cessation of smoking. TJ means tender joint counts and SJ means swollen joints counts for the assessment of DAS 28-CRP.