Rheumatoid Arthritis, Kartagener’s Syndrome, and Hyperprolactinemia: Who Started It?

Table 1

Summary of reported cases and patient characteristics.

Case report	Race	Age	Sex	Other comorbidities	RF or ACPA	HLA type	Erosions	Other X-ray findings	Treatment received
Kawasaki et al. 2000 [6]	Japan	11	M	None	Negative	—	—	—	MTX, Prednisolone, and NSAIDS (doses not mentioned) and then later MTX changed to Bucillamine
Riente et al. 2001 [7]	Italy	60	F	DM, HTN, heart failure	Positive	A1, B44, B51, DRB111; DRB116; DRB3, DRB5	No	Symmetric narrowing of MCP + PIP with juxta-articular osteoporosis	Initially Chloroquine 500 mg/day orally; + Methylprednisolone 4 mg/d; Then Gold IM, low dose steroids + antibiotics
Rébora et al. 2006 [9]	Argentina	38	F	None	Positive	(i) A1, B8, B57; (ii) HLA DR not studied	Yes	Narrowing at the wrists + 3rd MCPs bilaterally with juxta-articular osteopenia	Initially SSZ 1.5 g per day + NSAIDS; Later Chloroquine 200 mg and then HCQ 400 mg daily; Subsequently shifted to MTX 15 mg/day
Younes et al. 2006 [8]	Tunisia	35	F	None	Positive	—	Yes	Narrowing at the MCPs + 2nd & 3rd PIPs	Indomethacin 100 mg daily, Prednisolone 10 mg orally daily and MTX 10 mg weekly later increased to 15 mg weekly
Takasaki et al. 2014 [10]	Japan	47	F	Periodontitis, smoker	Positive	—	Yes	Joint destruction in the RT thumb MCP + LT thumb MCP and PIP	MTX 12 mg weekly, Tacrolimus 2 mg/daily, Prednisone 4 mg daily; Later shifted to Etanercept 50 mg/week + tacrolimus tapered off
Our patient	Saudi Arabia	18	F	—	Positive	—	No	Normal	MTX 12.5 mg PO weekly gradually increased until 20 mg weekly + Prednisolone 15 mg orally daily gradually tapered off

MTX = Methotrexate, HCQ = Hydroxychloroquine, and SSZ = sulfasalazine.