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Case Reports in Rheumatology
Volume 2017, Article ID 1891897, 3 pages
Case Report

A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer

1Internal Medicine Department, Hôpital de la Tour, Geneva, Switzerland
2Department of Pathology, Geneva University Hospitals, Geneva, Switzerland
3Department of Rheumatology, Geneva University Hospitals, Geneva, Switzerland

Correspondence should be addressed to Simon Ponthus; moc.liamg@suhtnop.nomis

Received 3 February 2017; Accepted 22 February 2017; Published 8 March 2017

Academic Editor: Tamás Constantin

Copyright © 2017 Simon Ponthus et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We report the case of a 64-year-old woman with an atypical first presentation of NAM, manifested by chest pain in the context of metastatic endometrial cancer. The diagnosis of NAM was however made when she returned a second time with proximal limb weakness. A treatment with prednisone was then initiated, to which rituximab was rapidly associated, beside a specific chemotherapy.