Improvement of Arterial Wall Lesions in Parallel with Decrease of Plasma Pentraxin-3 Levels in a Patient with Refractory Takayasu Arteritis after Treatment with Tocilizumab

Figure 1

Changes in disease activity, biomarkers, and treatment during anticytokine biologic therapy. Infliximab (IFX) was administered at a dose of 6 mg per kilogram of body weight every four weeks (white bar). Intravenous tocilizumab (TCZ-IV) was administered at a dose of 8 mg per kilogram of body weight every four weeks (black bar), and subcutaneous tocilizumab (TCZ-SC) was administered at a dose of 162 mg per body weight every other week (gray bar). CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; IL-6, interleukin-6; ITAS2010, The Indian Takayasu Activity Score 2010; PSL, prednisolone; PTX3, pentraxin-3.