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Case Reports in Rheumatology
Volume 2018, Article ID 6150875, 6 pages
Case Report

Axial Spondyloarthritis and Autosomal Dominant Polycystic Kidney Disease in Two Siblings: A Rare Cooccurrence

1Department of Physical Medicine and Rehabilitation, Bezmialem Foundation University, Istanbul, Turkey
2Department of Nephrology, Gaziosmanpasa Taksim Training and Research Hospital, Istanbul, Turkey

Correspondence should be addressed to Ozan Volkan Yurdakul; moc.oohay@nazo_lukadruy

Received 4 January 2018; Revised 31 January 2018; Accepted 7 February 2018; Published 4 March 2018

Academic Editor: Constantine Saadeh

Copyright © 2018 Ozan Volkan Yurdakul et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Autosomal dominant polycystic kidney disease (ADPKD) is the most frequently occurring hereditary kidney disease, and axial spondyloarthritis (SpA) is one of the most frequently occurring rheumatic diseases. Treatment-related decisions for axial SpA may pose a challenge in case of renal involvement. The authors describe two siblings with cooccurrence of these two diseases. The association of these two diseases is not well known. Practitioners should monitor renal function in SpA patients and take treatment-related decisions regarding renal involvement. Antitumor necrosis factor-alpha (anti-TNF-α) agents may be used in case nonsteroidal anti-inflammatory drugs (NSAIDs) cannot be utilized.