Sjögren Syndrome Complicated with Cystic Lung Disease and Pulmonary Amyloidosis

Figure 2

Pathologic findings of the surgical lung biopsy in a 72-year-old woman with Sjögren syndrome and pulmonary amyloidosis. (a) There is a homogeneous eosinophilic material in the vascular area (hematoxylin and eosin stain, ×100), which (b) was positive on Congo red stain (×100). (c) Polarizing microscopy shows apple green birefringence (×100). (d) The immunohistochemical staining with AA amyloid (×100) was negative. (e) The immunohistochemical staining with AL-kappa amyloid (×100) was positively stained. (f) There is infiltration of inflammatory cells in the peribronchial areas (hematoxylin and eosin stain, ×100).