Nephrotic Syndrome due to Focal Segmental Glomerulosclerosis Complicating Sjögren’s Syndrome: A Case Report and Literature Review

Table 1

Main laboratory data of the current case.

Blood analysis
WBC	8190	/μL	C3	67	mg/dL
RBC	4100000	/μL	C4	15	mg/dL
Hb	12.3	g/dL	CH50	34.1	U/mL
Plt	208000	/μL	CRP	0.43	mg/dL
TP	6.3	g/dL	IgG	1440	mg/dL
ALB	1.7	g/dL	IgA	415	mg/dL
ChE	369	U/L	IgM	1565	mg/dL
T.Ch	323	mg/dL	Cryoglobulins	(–)
TG	233	mg/dL	Serum immunofixation M protein	(–)
AST	65	U/L	pH	7.48
ALT	33	U/L	PaCO2	30.3	mmHg
LDH	392	U/L	PaO2	59.8	mmHg
ALP	1235	U/L	Bicarbonate	22.3	mmol/L
γ-GT	664	U/L	Osmolarity	292	mOsm/kg
BUN	14.9	mg/dL	Anti-nuclear antibody	2560	(speckled)
Cr	0.65	mg/dL	Anti-mitochondria M2 antibody	20.6 (+)
UA	5.7	mg/dL	Anti-double stranded DNA antibody	(–)
Na	140	mmol/L	Anti-ribonucleoprotein antibody	(–)
K	3.9	mmol/L	Anti-SS-A/Ro antibody	(–)
Cl	110	mmol/L	Anti-SS-B/La antibody	(–)
Ca	7.5	mg/dL	Anti-scleroderma-70 antibody	(–)
iP	3.7	mg/dL	Anti-Jo-1 antibody	(–)
Mg	2.5	mg/dL	Anti-centromere antibody	(–)
Urinalysis
pH	6.0		UUA	62.6	mg/dL
UP	(3+)		UNa	39	mEq/L
OB	(–)		UK	34	mEq/L
NAG	129.3	U/L	UCl	38	mEq/L
β2-MG	2539	U/L	UCa	1.0	mg/dL
Osmolarity	408	mOsm/kg	UiP	47.6	mg/mL
UUN	579.3	mg/dL
UCr	116.9	mg/dL

WBC: white blood cells; RBC: red blood cells; Hb: hemoglobin; Plt: platelet; TP: total protein; ALB: albumin; ChE: cholinesterase; T.Ch: total cholesterol; TG: triglycerides; AST: aspartate aminotransferase; ALT: alanine aminotransferase; LDH: lactate dehydrogenase; ALP: alkaline phosphatase; γ-GT: gamma-glutamyltransferase; BUN: blood urea nitrogen; Cr: creatinine; UA: uric acid; Na: sodium; K: potassium; Cl: chloride; Ca: calcium; iP: inorganic phosphorus; Mg: magnesium; C3: complement 3; C4: complement 4; CH50: 50% hemolytic complement activity; CRP: C-reactive protein; IgG: immunoglobulin G; IgA: immunoglobulin A; IgM: immunoglobulin M; UP: urinary protein; OB: occult blood; NAG: N-acetyl-beta-D-glucosaminidase; β2-MG: beta-2-microglobulin; UUN: urine urea nitrogen; UCr: urine creatinine; UUA: urine uric acid; UNa: urine sodium; UK: urine potassium; UCl: urine chloride; UCa: urine calcium; UiP: urine inorganic phosphorus.