Case Reports in Rheumatology / 2019 / Article / Tab 1

Case Report

The Central Nervous System Effects and Mimicry of Common Variable Immunodeficiency (CVID): A Case Report with Literature Review

Table 1

Case report MRI findings, treatment, and outcome.

AuthorMRI findingsTreatmentOutcome

Farshad et al.Spine: hyperintensity in the thoracic cordChronic glucocorticoids without pulseImprovement in MRI findings
Brain: hyperintensity within the right middle frontal gyrusMethotrexatePersistent neurological symptoms
IVIG

Jabbari et al. [2]Spine: hyperintensity between T2 and conus medullaris with contrast enhancementPulse glucocorticoids without a taper/chronic glucocorticoidsImprovement in MRI findings
Brain: unremarkableIVIGResolution of neurological symptoms
Inpatient rehabilitation

Kumar et al. [3]Spine: hyperintensity in the cervical and thoracic cord with contrast enhancementPulse glucocorticoids followed by chronic taperImprovement in MRI findings
Brain: contrast enhancement in the right basal forebrainInfliximabPersistent neurological symptoms
IVIG

Danieli et al. [4]Spine: hyperintensity in the cervical and thoracic cord with contrast enhancementPulse glucocorticoids without a taper/chronic glucocorticoidsNo new lesions in MRI after treatment, unclear if resolved
Brain: unremarkableIVIGPersistent neurological symptoms
Intramuscular immunoglobulin

Nguyen et al. [5]Spine: was not obtainedPulse glucocorticoids without a taper/chronic glucocorticoidsImprovement in MRI findings
Brain: two enhancing lesions in left cerebellum as well as leptomeningeal enhancementRituximabImprovement/near resolution of neurological symptoms
IVIG

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