Primary Sjögren’s Syndrome Accompanied by Clinical Features of TAFRO Syndrome

Table 2

Comparison summary of previous cases of Sjögren’s syndrome complicated with clinicopathologic features of TAFRO syndrome.

Authors			Iwanaga et al.	Fujimoto et al.	Takasawa et al.	Li et al.	Kojima et al.	Our case
Sjögren’s syndrome		Histopathology	+	+	ND	ND	ND	ND
		Oral examination	+	Scintigraphy	ND	ND	ND	+
		Ocular examination	+	+	+	ND	ND	−
		Anti-Ro/SS-A antibody	+	+	+	+	+	+
		Anti-La/SS-B antibody	−	+	−	ND	+	+
TAFRO syndrome	Major categories	Anasarca	+	+	+	+	+	+
		Thrombocytopenia	+	+	+	+	+	+
		Systemic inflammation	+	+	+	+	+	+
	Minor categories	Histology of lymph node biopsy	−	+	+	+	+	ND
		Reticulin myelofibrosis	+	+	+	+	ND	−
		Mild organomegaly	+	+	+	+	+	+
		Renal insufficiency	−	+	+	+	ND	±
Treatments			PSL, CyA	PSL	PSL, CyA	Siltuximab, PSL, RTX, CY, vincristine	PSL	PSL, CyA, eltrombopag

CY, cyclophosphamide; CyA, cyclosporine; PSL, prednisolone; RTX, rituximab; ND, not determined.