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Case Reports in Surgery
Volume 2012, Article ID 165319, 4 pages
http://dx.doi.org/10.1155/2012/165319
Case Report

Primary Cutaneous Melanoma Arising in a Long-Standing Irradiated Keloid

1Department of Surgery, University of Tennessee Graduate School of Medicine, Knoxville, TN 37920, USA
2Department of Pathology, University of Tennessee Graduate School of Medicine, Knoxville, TN 37920, USA

Received 27 September 2011; Accepted 19 October 2011

Academic Editors: M. Gorlitzer and C. Suárez Nieto

Copyright © 2012 Lindsay M. Fish et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Ionizing radiation has been used therapeutically for a variety of clinical conditions, including treatment of hypertrophic keloids. Keloids may rarely be associated with malignancy, but the use of low-dose ionizing radiation is associated with an increased risk of cutaneous malignancies. We describe a case in which a primary desmoplastic melanoma arose in a long-standing, previously irradiated keloid.