Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
Figure 4
Immunohistochemical staining shows that majority of the tumor cells are strongly positive for alpha-fetoprotein (αFP) ((a): ×400) and negative for beta subunit of human chorionic gonadotropin (βHCG) ((b): ×100). They are strongly positive for wide-spectrum cytokeratin ((c): ×100), BerEP4 ((d): ×100), partially positive for CD117 (c-kit) ((e): ×200), and negative for CD30 ((f): ×100).
