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Case Reports in Surgery
Volume 2015, Article ID 412918, 4 pages
http://dx.doi.org/10.1155/2015/412918
Case Report

Carcinosarcoma of the Rectum: Report of a Rare Colorectal Malignancy and Review of the Literature

1Department of Colorectal Surgery, James Paget University Hospital, Gorleston NR31 6LA, UK
2Department of Histopathology, Norfolk and Norwich University Hospital, Norwich NR4 7UY, UK

Received 25 August 2015; Accepted 29 October 2015

Academic Editor: Paola De Nardi

Copyright © 2015 Alexis Sudlow et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Carcinosarcoma (CS) is a rare mixed mesodermal malignancy most commonly affecting the female reproductive organs, respiratory tract, head, and neck. Though infrequent, it may affect the gastrointestinal tract, most often the oesophagus and only very rarely the rectum. Histologically, it is composed of two distinct elements of epithelial and mesenchymal origin. Clinically, it is a very aggressive tumour with many patients presenting with metastatic lymph nodes or distant metastases at the time of diagnosis. Prognosis is poor despite intervention with the majority of patients dying within six months. Due to the rarity of this condition, there are no specific treatment guidelines presently available. We describe the case of an 80-year-old patient with carcinosarcoma of the rectum with discussion of the immunohistochemistry and review the available literature pertaining to this rare presentation.