Primary Left Cardiac Angiosarcoma with Mitral Valve Involvement Accompanying Coronary Artery Disease

Figure 2

Intraoperative situs with view through the intra-atrial septum (transseptal approach). The arrow marks the roughly 1 cm large tumour originating at the posterior leaflet of the mitral valve (a). Haematoxylin and Eosin stain displaying a tumour consisting of irregular neoplastic vascular channels surrounded by atypical spindle shaped and epithelioid tumour cells (×40) (b). In immunohistochemical staining the tumour cells are stained with CD31 (×40) (c) and focally with Pan CK (×20) (d) and S-100 (×20) (e). The cells are pleomorphic and atypical.

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(b)

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