Case Report

Delayed Guillain-Barré Syndrome after Bariatric Surgery: A Report of Three Cases

Table 1

Review of literature: GBS case reports after bariatric surgeries.

Name and authorYearCountryStudy typeTreatmentOutcome

Guillain-Barré-like syndrome after bariatric surgery [5] Natalia Bodunova2015RussiaCase reportVitamin B complex (milgamma), thiamine, pyridoxine, and ferrous sulfateThe neurological symptoms stabilized when treatment was initiated. Over the next several months, the symptoms gradually improved; he required the assistance of a walker for 6 months before his symptoms completely resolved.
Guillain-Barré syndrome and postbariatric surgery polyneuropathies [6] Kanayochukwu J. Aluka2009Washington, DC, USACase reportGabapentin, physical therapySymptoms gradually improved; she required the assistance of a walker for 6 months before her symptoms completely resolved.
Guillain-Barré syndrome (demyelinating) six weeks after bariatric surgery: a case report and literature review [10] N. Ishaque2015Karachi, PakistanCase reportIntravenous immunoglobulin (IVIG) and rehabilitationShe had complete recovery on follow-up.
Weakness after gastric bypass [7] Craig G. Chang2002Los Angeles and Kansas City, USACase seriesFirst patient: plasmapheresis. Therapy was changed to intravenous immunoglobulin G (for 1 year)
Second patient: IVIG
First patient: regained some strength in her legs but is confined to a wheelchair because of uncontrollable shaking and persistent weakness of her upper limb.
Second patient: improvement in sensation and strength after second dose of IVIG was discharged to the rehabilitation unit and after 8 weeks was at her baseline premorbid ambulatory status.
Neurological complications of bariatric surgery [9] Hussein A. Algahtani2016Jeddah, Saudi Arabia451 patients who underwent bariatric surgeryFourteen patients had full recovery from the neurological signs and symptoms; one patient died.
Acute axonal polyneuropathy with predominant proximal involvement: an uncommon neurological complication of bariatric surgery [11] Flavia Costa Nunes Machado2006São Paulo, BrazilCase reportVitamin supplementation (B1 and B6 vitamin) and IVIGRapidly recovered proximal muscle strength.
Neurological complications of bariatric surgery [12] Anne Landais2014Abymes, FranceCase seriesFirst patient: IV thiamine replacement therapy, followed by intramuscular thiamine daily and physiotherapy
Second patient: IV vitamin B1 and physiotherapy
First patient: after a few days of treatment, there was a slight improvement in gait disorders. She slowly but progressively improved after physiotherapy, and 6 months later, she had nearly completely recovered.
Second patient: there was an improvement of the neurological problems following vitamin B1 supplementation. He was seen 5 months later; motor improvement was equally limited. The patient was able to stand and walk a few meters but needed a wheelchair for long distances.
Rare neurological complication of bariatric surgery: acute motor axonal neuropathy (AMAN), a severe motor axonal form of Guillain-Barré syndrome [13] AF Landais2014FranceCase reportIVIGSeven days after initiation of treatment, she was transferred to the rehabilitation department.