Solid Pseudopapillary Neoplasm of the Pancreas with High-Grade Malignant Transformation Involving p16-RB Pathway Alterations

<div>Computed tomography (CT) images and surgical specimens. (a) Abdominal CT showing similar large solid masses with cystic components in the pancreatic tail and right hepatic lobe. (b) Macroscopic cross-section of the pancreatic tumour revealing a bulky mass (<i>φ</i>10 cm) that consists of a cystic component containing extensive haemorrhagic, friable necrotic debris, and a white-to-grey solid component showing lobular growth. Liver metastatic foci also show similar macroscopic findings (inset).</div>

Case Reports in Surgery

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Figure 1

Figure 1: Solid Pseudopapillary Neoplasm of the Pancreas with High-Grade Malignant Transformation Involving p16-RB Pathway Alterations 