De Novo Collapsing Glomerulopathy: An Unusual Cause of Early Graft Failure following Kidney Transplantation
(a) Collapsed glomerular capillary loops with obliteration of vascular spaces are noted. Podocyte hyperplasia and synechiae formation along with tubular atrophy are evident (Hematoxylin-eosin 100x),(b) high-power view showing prominent collapse of glomerular tuft with obliteration of vascular spaces along with pseudocrescent formation (Jones-Silver stain 400x), and (c) electron microscopy showing collapse of the glomerular tuft with basement membrane wrinkling, podocyte enlargement, and effacement of foot processes. No tubuloreticular inclusions in endothelial cells are seen (2,950x).
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.