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Case Reports in Transplantation
Volume 2013, Article ID 407875, 2 pages
Case Report

Mitral Valve Regurgitation: A Severe Complication following Left Ventricular Biopsy 15 Years after Heart Transplantation

Department of Cardiac Surgery, Heartcenter Leipzig University, Struempellstraße 39, 04289 Leipzig, Germany

Received 16 January 2013; Accepted 18 February 2013

Academic Editors: J. A. Kari and J. S. Kim

Copyright © 2013 Marcel Vollroth et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 71-year-old male patient underwent orthotopic heart transplantation in 1995. Due to left heart catheterization 15 years later, biopsy from the left ventricular apex was performed for rejection screening. Two days later, echocardiography revealed severe mitral valve regurgitation requiring mitral valve replacement. This is a very rare case showing that left heart biopsy may lead to severe hemodynamic complications with the need for surgical intervention.