Treatment of Cytomegalovirus Infection with Cidofovir and CMV Immune Globulin in a Lung Transplant Recipient

Figure 1

Schematic of CMV treatment, CMV-DNA, and pp65 levels over time. The absence and presence of CMV-specific CD4⁺ T-cells as determined by flow cytometry are indicated by (−) and (+) symbols. CMV-DNA was quantified from whole blood using the Cobas-Amplicor-assay (Roche Diagnostics) with a clinically relevant detection limit of 450 copies/mL. A cut-off of CMV-specific CD4⁺ T-cells of ≥0.05% was considered positive.