Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Transplantation
Volume 2017, Article ID 1084718, 3 pages
https://doi.org/10.1155/2017/1084718
Case Report

Unusual Pathology in a Kidney from a Heart-Transplant Patient

1Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France
2Department of Pathology, Institut du Cancer de Toulouse, Toulouse, France
3Université Paul Sabatier, Toulouse, France
4Department of Cardiology, CHU Rangueil, Toulouse, France
5Department of Heart Surgery, CHU Rangueil, Toulouse, France
6INSERM U1043, IFR–BMT, CHU Purpan, Toulouse, France

Correspondence should be addressed to Nassim Kamar; rf.esuoluot-uhc@n.ramak

Received 25 August 2017; Revised 10 October 2017; Accepted 18 October 2017; Published 5 November 2017

Academic Editor: Frieder Keller

Copyright © 2017 Marie Larcher et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Acute kidney injury (AKI) is often observed after heart transplantation. In this setting, acute tubular necrosis is the main histological finding on kidneys. We report the unusual pathology found in a kidney from a heart-transplant patient. The patient experienced several hemodynamic insults, massive transfusion, and implantation of a mechanical circulatory-support device before heart transplantation: there was prolonged AKI after transplantation. A kidney biopsy revealed acute tubular necrosis and renal hemosiderosis, which was probably related to the transfusion and to mechanical circulatory-support device-induced intravascular hemolysis. Assessment of iron during resuscitation could have prevented, at least partly, AKI.