TY - JOUR
A2 - Srinivas, S.
A2 - Hong, S. K.
AU - Charfi, Nadia
AU - Kamoun, Mahdi
AU - Feki Mnif, Mouna
AU - Mseddi, Neila
AU - Mnif, Fatma
AU - Kallel, Nozha
AU - Ben Naceur, Basma
AU - Rekik, Nabila
AU - Fourati, Hela
AU - Daoud, Emna
AU - Mnif, Zainab
AU - Hadj Sliman, Mourad
AU - Sellami-Boudawara, Tahia
AU - Abid, Mohamed
PY - 2012
DA - 2012/02/12
TI - Leydig Cell Tumor Associated with Testicular Adrenal Rest Tumors in a Patient with Congenital Adrenal Hyperplasia due to 11-Hydroxylase Deficiency
SP - 648643
VL - 2012
AB - Congenital adrenal hyperplasia (CAH) describes a group of inherited autosomal recessive disorders characterized by enzyme defects in the steroidogenic pathways that lead to the biosynthesis of cortisol, aldosterone, and androgens. Chronic excessive adrenocorticotropic hormone (ACTH) stimulation may result in hyperplasia of ACTH-sensitive tissues in adrenal glands and other sites such as the testes, causing testicular masses known as testicular adrenal rest tumors (TARTs). Leydig cell tumors (LCTs) are make up a very small number of all testicular tumors and can be difficult to distinguish from TARTs. This distinction is interesting because LCTs and TARTs require different therapeutic approaches. Hereby, we present an unusual case of a 19-year-old patient with CAH due to 11β-hydroxylase deficiency, who presented with TARTs and an epididymal Leydig cell tumor.
SN - 2090-696X
UR - https://doi.org/10.1155/2012/648643
DO - 10.1155/2012/648643
JF - Case Reports in Urology
PB - Hindawi Publishing Corporation
KW -
ER -