|
| Serial number | Author and year | Age | Gender | Sodium level at diagnosis
(mmol/L) | Amiodarone dose and duration | Time to develop hyponatremia | Management | Day on which serum sodium normalized |
|
|
1 |
Ruiz et al. 1996 [8]
| 67 | F | 110 | Not mentioned | 4 Months | Discontinuation | Unknown |
|
2 |
Odeh et al. 1999 [7] | 62 | F | 120 | 300 mg qd | 6 Months | Discontinuation | 5 Days |
|
3 |
Patel and Kasiar 2002 [9]
| 67 | M | 117 | 200 mg qd | 3 Months | Fluid restriction, Discontinuation of therapy | 3 Days |
|
4 |
Ikegami et al. 2002 [11]
| 63 | M | 119 | 800 mg qd | 7 Days | Amiodarone dose reduced to 100 mg qd, fluid restriction | 28 days |
|
5 |
Ikegami et al. 2002 [11]
| 87 | M | 121 | 200 mg qd for seven days then 100 mg qd | 15 Days | Fluid restriction only | 14 Days |
|
6 |
Aslam et al. 2004 [10]
| 72 | M | 117 | 2 g qd (loading dose) | 5 Days | Decrease dose to 200 mg qd | Normalized on 2nd day, Stable on 14th day |
|
7 |
Paydas et al. 2008 [12]
| 58 | M | 107 | Not mentioned | 5 Months | Cessation of treatment | 14 Days |
|
8 |
Shavit and sherer 2007 [13]
| 85 | M | 122 | Not mentioned | 30 Days | Cessation of treatment | A few days, stable at 3rd month |
|
9 |
Singla et al. 2013 [14]
| 66 | M | 120 | Loading followed by 400 mg four times a day | 3 Days | Discontinuation of amiodarone and hemodialysis | Not Mentioned |
|
10 |
Afshinnia et al. 2011 [15]
| 72 | M | 117 | 150 mg IV loading, 900 mg over 24 hours, 400 mg TDS | 7 days | | 16 Days |
|
11 |
Pham et al. 2013 [16]
| 84 | M | 105 | Loading followed by 400 mg 8 hourly ×3 days. Then 400 mg OD | 11 Days | Hypertonic saline, Fluid restriction, Demichlocycline, | 10 Days |
|
12 | Dutta et al. (Present Case) | 62 | M | 109 | 100 mg OD | 9 Months | Fluid restriction, stoppage of amiodarone | 3 Days |
|
