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Case Reports in Urology
Volume 2014 (2014), Article ID 259870, 3 pages
http://dx.doi.org/10.1155/2014/259870
Case Report

Persistent High Level of Urinary Tumor Marker Carbohydrate Antigen 19-9 in Prenatally Diagnosed Dysplastic Kidney

1Pediatric Urology Research Center, Children’s Hospital Medical Center, Pediatric Center of Excellence, Tehran University of Medical Science, No. 62, Dr. Gharib’s Street, Keshavarz Boulevard, Tehran 1419733151, Iran
2Department of Obstetrics and Gynecology, Mirza Koochackkhan Women’s Sciences Hospital, Tehran University of Medical Science, Tehran 1419433151, Iran

Received 26 November 2014; Accepted 17 December 2014; Published 31 December 2014

Academic Editor: Fumitaka Koga

Copyright © 2014 Reza Khorramirouz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Tumor marker carbohydrate antigen 19-9 (CA 19-9) level has gained clinical significance in gastrointestinal malignancies and in various solid and cystic diseases. Dysplastic kidney is a congenital abnormality resulting from atresia of the ureteral bud during the embryogenesis which can be unilateral or bilateral. We report unilateral dysplastic kidney with extremely large cyst diagnosed by routine ultrasonography in the 32nd week of gestational age with high levels of CA 19-9 in cystic and amniotic fluid, as well as persistent high urinary levels of this tumor marker during the 1-year follow-up. Persistent high urinary CA 19-9 level even after cyst aspiration may be attributable to remained function of dysplastic kidney due to remained epithelial lining.