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Case Reports in Urology
Volume 2016, Article ID 6080859, 3 pages
http://dx.doi.org/10.1155/2016/6080859
Case Report

Primary Mucinous Adenocarcinoma of the Urinary Bladder with Signet-Ring Cells: Description of an Uncommon Case and Critical Points in Its Management

1Section of Urology, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy
2Section of Urology, Hospital Universitário da Universidade Federal do Piauì, Teresina, PI, Brazil
3Section of Oncology, Hospital Universitário da Universidade Federal do Piauì, Teresina, PI, Brazil

Received 17 August 2016; Revised 8 November 2016; Accepted 15 November 2016

Academic Editor: Apul Goel

Copyright © 2016 Fabrizio Di Maida et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We present an uncommon case of mucinous adenocarcinoma of the bladder (MAB) with signet-ring cells extensively infiltrating prostate gland and pelvic/retroperitoneal lymph node stations and not responsive to usual systemic chemotherapy regimens. This case highlights the important features of MAB including the pattern of tumor spread, the tendency for initial misdiagnosis, and the importance of immunohistochemical study in order to define its primary origin from the bladder and choose the most appropriate treatment since the beginning.