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Case Reports in Urology
Volume 2017, Article ID 1654231, 3 pages
https://doi.org/10.1155/2017/1654231
Case Report

PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings

1Departments of Urology, University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
2Departments of Pathology, University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
3Departments of Nuclear Medicine, University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
4Departments of Radiologic Diagnostics, University Hospital “Carl Gustav Carus”, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany

Correspondence should be addressed to Michael Froehner; ed.nedserd-mukinilkinu@renheorf.leahcim

Received 30 November 2016; Revised 27 February 2017; Accepted 5 March 2017; Published 15 March 2017

Academic Editor: Apul Goel

Copyright © 2017 Michael Froehner et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A 67-year-old man diagnosed with Gleason score clinically localized prostate cancer with 68Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) positive Paget bone disease is described. Immunohistochemical staining revealed weak PSMA positivity of the bone lesion supporting the hypothesis that neovasculature might explain positive PSMA-PET/CT findings in Paget disease.