PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings

<div>CT-guided biopsy (a) showed irregular bone structure with fibrotic marrow spaces ((b) H&amp;E; original magnification ×20) containing multinucleated giant cells ((c) arrowheads; chloroacetate esterase stain; original magnification ×20). Immunohistochemical staining for PSMA revealed weak PSMA expression in endothelial cells ((d) arrowhead; original magnification ×20) in the Paget bone lesion.</div>

Case Reports in Urology

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Figure 2: PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings 