Case Report

Unusual Presentation of Priapism Associated with Acute and Chronic Myeloid Leukemia in Two Patients: Emergency Management

Table 1

Literature review of priapism and leukemia from 2003 to 2020 using the PubMed database.

SeriesAgeDiagnosisPresenting symptomsWBC cell/mm3Platelet count cell/mm3Treatment of priapism and leukemiaOutcome

Becerra-Pedraza et al. [2]52 yrsChronic myeloid leukemiaPriapism for 144 hrs, fatigue, pallor282 000Corpora cavernosa drainage-irrigation penile shunts. DasatinibNo ED on follow-up
Hazra et al. [3]14 yrsChronic myeloid leukemiaPriapism for 24 hrs226 900310 000Cavernosal aspiration and phenylephrine irrigationNo recurrence at 2-month follow-up
Khan et al. [5]16 yrsChronic myeloid leukemiaPriapism for 264 hrs614 8007 090 000Glans-cavernosal shunt hydroxyurea and allopurinolAchieved detumescence. No info on ED
Nerli et al. [8]19 yrsChronic myeloid leukemiaPriapism for 24 hrs296 800936 000Corporal aspiration and phenylephrine irrigation hydroxyurea and imatinibAchieved detumescence. No info on ED
Minckler et al. [9]18 yrsChronic myeloid leukemiaRecurrent priapism5 880 0001 090 000Hydroxyurea and imatinibNo info on follow-up
Chang et al. [10]21 yrsChronic myeloid leukemiaPriapism for 19 hrs216 8001 746 000Cavernosa aspiration and epinephrine irrigation hydroxyurea and interferonNo ED on follow-up
Qu et al. [11]18 yrsChronic myeloid leukemiaPriapism for 72 hrs257 0005 450 000Cavernosa-corpus spongiosum shunt, imatinibNo ED at 3-month follow-up
Yoshida et al. [12]29 yrsChronic myeloid leukemiaPriapism for 48 hrs263 000Glans-cavernosal shunt hydroxyurea and imatinibNo ED at 5-month follow-up
Tazi [13]33 yrsChronic myeloid leukemiaPriapism for 22 hrs400 0001 200 000Cavernosa aspiration and epinephrine irrigationNo recurrence on follow-up
Ponniah et al. [14]19 yrsChronic myeloid leukemiaPriapism for 18 hrs513 000Failed cavernosal aspiration + leukapheresisNo ED on follow-up
Ergenc et al. [15]18 yrsChronic myeloid leukemiaPriapism for 72 hrs100 0001 002 000İmatinib, allopurinol + leukapheresisNo ED at 6-month follow-up
Gupta et al. [16]10 yrsAcute lymphoblastic leukemiaPriapism, fever, headache693 00040 000Corporal aspiration followed by phenylephrine irrigation, allopurinol + steroidsDied after 48 hours
Güzelküçük et al. [17]9 yrsAcute lymphoblastic leukemiaPriapism for 18 hrs583 00051 000Corporal aspiration followed by hydroxyurea, allopurinol + leukapheresisAchieved detumescence

ED: erectile dysfunction; Hrs: hours; WBC: White Blood Cell; Yrs: years.