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Case Reports in Vascular Medicine
Volume 2014, Article ID 873402, 3 pages
http://dx.doi.org/10.1155/2014/873402
Case Report

Bilateral Jugular Vein and Sigmoid Sinus Thrombosis Related to an Inherited Coagulopathy: An Unusual Presentation

1Department of Neurology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey
2Department of Radiology, Medical Faculty, Bezmi Alem Vakıf University, Adnan Menderes Boulevard, Fatih, 34093 Istanbul, Turkey

Received 22 March 2014; Accepted 10 August 2014; Published 21 August 2014

Academic Editor: Atila Iyisoy

Copyright © 2014 Özge Altıntaş et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Internal jugular vein thrombosis (IJVT) is a rare condition associated with malignancy, coagulopathy, and trauma. The optimal management of any IJVT must be individualized and depends on the condition of the patient. Case Presentation. We report the case of a 42-year-old woman with a history of a first trimester spontaneous abortion. Apart from a tension-type headache, she had no neurological symptoms. She reported an incidental diagnosis of right-sided IJVT when she was evaluated for hyperthyroidism ultrasonographically. On ultrasonography, we observed bilateral jugular vein thrombosis. The patient was started on oral warfarin. Seven months later, when she was adequately anticoagulated, she developed a second thrombosis. According to the etiological workup, she had a mutation in the homozygous methylene tetrahydrofolate reductase (MTHFR) gene and reduced protein C levels and activity. Conclusion. This report illustrates an unusual presentation of a rare condition. In this case, the etiology was associated with the coagulopathy, which occurred despite adequate anticoagulation.