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Case Reports in Veterinary Medicine
Volume 2012, Article ID 301498, 5 pages
Case Report

Gastrointestinal Stromal Tumor in the Cecum of a Horse

1Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland
2Department of Equine Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland

Received 15 March 2012; Accepted 20 June 2012

Academic Editors: J. Carmalt, C. Hyun, J. S. Munday, and F. Mutinelli

Copyright © 2012 S. Stephan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Gastrointestinal stromal tumors (GISTs) are defined as specific CD117-(Kit, stem cell factor receptor) expressing tumors of the gastrointestinal (GI) tract. They are believed to originate from the interstitial pacemaker cells of Cajal (ICC) or their progenitor cells. In horses only a few cases of GISTs are described in the literature. In the present paper the macroscopical, histological, immunohistochemical, and ultrastructural features of an equine cecal GIST are described.