Case Report

A Case of Contagious Ecthyma (Orf Virus) in a Nonmanipulated Laboratory Dorset Sheep (Ovis aries)

Figure 5

Haired skin, lip commissure. Epithelial hyperplasia ( ) with increased thickness up to 10 times normal (acanthosis) with prominent intracellular clear spaces/bridging (spongiosis), anastomosing rete ridges, and a vesicle (arrow). Inset: rarely keratinocytes contain one or more 2–10 µm round, brightly eosinophilic intracytoplasmic inclusion bodies (arrowheads). Hematoxylin and eosin stain, 20x objective.
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