Failure of Miltefosine Treatment in Two Dogs with Natural Leishmania infantum Infection

Table 1

Case number 1: clinical score, therapy, and hematological and biochemical analysis of the first dog affected by canine leishmaniasis.

Followup	Clinical score	Therapy	RBC; ×10^3/L	Hb; g/dL	PCV%	PLT; /uL	TP; g/dL	ALB%	G%	A/G	IFAT
D0	8/86	MLT + A; 28/d	5220	12.6	34.8	37.000	9.3	31.7	42.7	0.46	1 : 1280
D30	3/86	A	5840	12.6	34.5	15.000	7.8	35.2	37.6	0.54	1 : 640
D60	2/86	A	6440	14.3	38.7	65.000	7.5	42.9	25.6	0.75	1 : 320
D90	0/86	A	6110	13.9	37.1	149.000	7.4	42.1	21.4	0.75	1 : 320
D150	11/86	MLT + A; 28/d	6350	14.2	40.5	232.000	8.3	41	31.7	0.6	1 : 640
D 210	0/86	A	6220	13.9	43.3	138.000	7.6	49.3	11.4	0.97	1 : 160
D240	2/86	MA; 28gg	6160	15	42.5	68.000	6.8	38.6	20.3	0.63	1 : 320
D270	0/86	A	5750	13.2	35.2	151.000	5.8	46.7	10.4	0.88	1 : 160
D330	0/86	A	6420	15.7	38.9	116.000	6.7	46.1	10	0.86	1 : 160
D390	0/86	A	6560	14	40.2	174.000	7.1	47.5	8.9	0.9	1 : 160
D660	1/86	—	6100	13.8	36.8	215.000	6.4	46.2	9.8	0.86	1 : 160