Case Reports in Veterinary Medicine / 2014 / Article / Tab 2

Case Report

Failure of Miltefosine Treatment in Two Dogs with Natural Leishmania infantum Infection

Table 2

Score for clinical parameters (on a scale from 0 to 86) used in dogs affected by canine leishmaniasis.

Clinical sign0123

AppetiteNormalSlight decreaseModerate decreaseAnorexia
MentationNormalSlight depressionDepressionProstration
LethargyNoSlightModerateRefusal to move
Weight lossNoSlightModerateSevere
PolyuriaNoSlightModerateSevere
PolydipsiaNoSlightModerateSevere
Localized muscular atrophy (temporal muscles)NoSlightModerateSevere
Generalized muscular atrophyNoSlightModerateSevere
LymphadenomegalyNo1-2 nodes2 > 4 nodesGeneralized
SplenomegalyNoYes
Conjunctivitis and/or blepharitisNoUnilateral and slightBilateral or unilateral severeBilateral and severe
Uveitis and/or keratitisNoUnilateral and slightBilateral or unilateral severeBilateral and severe
Pale mucous membranesNoSlightModerateSevere
EpistaxisNever presentedSporadicFrequentIncoercible
Mouth ulcers or nodulesNo1 or 2 small ulcers or nodules>2 small ulcers or nodules>1/4 or oral mouth cover by ulcers or nodules
VomitingNoSporadicFrequentFrequent with blood
DiarrheaNoSporadicFrequentConstant
LamenessNoSporadicFrequentConstant
ItchingNoSporadicFrequentConstant
ErythemaNo<10% body surface or slight generalized erythema10–25% body surface or moderate generalized erythema>25% body surface
Dry exfoliative dermatitisNo<10% body surface or slight generalized erythema10–25% body surface or moderate generalized erythema>25% body surface
Ulcerative dermatitisNo1-2 ulcers3–5 ulcers>5 ulcers
Nodular dermatitisNo1-2 nodules3–5 nodules>5 nodules
Sterile pustular dermatitisNo1-2 pustules3–5 pustules>5 pustules
AlopeciaNo<10% body surface10–25% body surface erythema>25% body surface
Altered pigmentationNoLocalizedMultifocalGeneralized
Hyperkeratosis of nasal planum and padsNoSlightModerateSevere
Generalized hyperkeratosisNoSlightModerateSevere
OnychogryphosisNoSlightModerateSevere

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.