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Case Reports in Veterinary Medicine
Volume 2014, Article ID 915808, 5 pages
Case Report

Bilateral Telencephalic Gliomatosis Cerebri in a Dog

1“Pingry” Veterinary Hospital, Via Medaglie d’Oro 5, 70126 Bari, Italy
2Department of Biopathological Science and Hygiene of Food and Animal Productions, Faculty of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy

Received 16 August 2014; Accepted 26 September 2014; Published 19 October 2014

Academic Editor: Paola Roccabianca

Copyright © 2014 Mario Ricciardi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An 8-year-old intact male Lagotto Romagnolo was presented with forebrain signs. Neuroanatomic localization was diffuse prosencephalon. MRI revealed diffuse, bilateral, and symmetric T2 and FLAIR hyperintensities in the parieto-occipital white matter and corpus callosum. No mass effect or contrast enhancement was noted. Analysis of cerebrospinal fluid revealed normal protein content and mild mononuclear pleocytosis. Atypical cells were not identified. 15 days later because of the worsening of clinical condition the patient was euthanized upon owner’s request. Neuropathological investigations were consistent with gliomatosis cerebri (GC). Such an unusual imaging pattern appeared similar to some cases of human GC and to a previous reported case in a dog, suggesting a possible repeatable imaging findings for this rare brain neoplasm. GC should be included in the MRI differentials for diffuse bilateral white matter signal changes and specific MRI findings described in this report may help in reaching a presumptive diagnosis of this tumor.