Bilateral Telencephalic Gliomatosis Cerebri in a Dog

Figure 4

(a) Brain tissue. Diffuse infiltration of the white matter by neoplastic cells having elongate nuclei and fibrillary cytoplasm. The neuropile shows a finely fibrillary pattern (H&E, ×20). (b) Brain tissue. The neoplastic cells show a diffuse marked immunoreaction for glial fibrillary acidic protein. They are characterized by long branched cytoplasmic processes (antiglial fibrillary acidic protein-immunolabeling, ×10).

(a)

(b)