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Canadian Respiratory Journal
Volume 7 (2000), Issue 1, Pages 71-76
Modern Classics

Regional Distribution of Gas in the Lung

Joseph Milic-Emili

Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada

Copyright © 2000 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In 1966, a paper entitled "Regional distribution of gas in the lung" was published in the Journal of Applied Physiology and became one of the 100 most-cited papers of clinical research from 1961 to 1978. The senior author provides the background and state-of-the art at the time of its publication, and reviews the main findings of the paper and subsequent developments.