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Canadian Respiratory Journal
Volume 8, Issue 6, Pages 431-433
Case Report

Primary Lymphoepithelioma-Like Carcinoma of Lung

Alejandro Guerrero,1 Michael Laflamme,2 S Nicholas Agoff,2 William M Williams,2 and Riyad Karmy-Jones1

1Department of Surgery, Division of Cardiothoracic Surgery, University of Washington, Seattle, Washington, USA
2Department of Pathology, Harborview Medical Center, Seattle, Washington, USA

Copyright © 2001 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary lymphoepithelioma-like carcinoma (LELC) of the lung is a neoplasm seen most commonly in the nasopharynx of individuals from south China and Taiwan, and is strongly associated with the Epstein-Barr virus. The case of a 62-year-old Chinese man with a rare primary lung T2N1M0 LELC of the left lower lobe is presented. The lesion was further notable because of the presence of necrotizing granulomatous inflammation. The patient was treated with surgical resection. After it was determined that the neoplasm was of primary lung origin, adjunctive chemotherapy was initiated. The role of adjunctive chemotherapy in this setting is discussed.