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Canadian Respiratory Journal
Volume 11, Issue 4, Pages 311-312
Case Report

High Dose Intravenous Methylprednisone in the Treatment of Severe Acute Respiratory Syndrome

Sharmistha Mishra,1 Winnie M Lee,1 Brian Bressler,1 Stephen C Juvet,1 and Denis Hadjiliadis2

1Department of Medicine, University of Toronto, Toronto, Ontario, Canada
2Division of Respirology, University of Toronto, Toronto, Ontario, Canada

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The case of a 72-year-old woman with probable severe acute respiratory syndrome is reported. While on treatment with ribavirin and antibiotics (for community-acquired pneumonia), the patient continued to have progressive clinical deterioration and chest radiographic evidence of respiratory deterioration. Pulse dose intravenous corticosteroids were used in an unsuccessful attempt to treat the inflammatory component of this respiratory illness.