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Canadian Respiratory Journal
Volume 18, Issue 3, Pages 144-148
http://dx.doi.org/10.1155/2011/430317
Original Article

Heterogeneity of Bronchitis in Airway Diseases in Tertiary Care Clinical Practice

Liesel D’silva, Nesreen Hassan, Hong-Yu Wang, Melanie Kjarsgaard, Ann Efthimiadis, Frederick E Hargreave, and Parameswaran Nair

Firestone Institute for Respiratory Health, St Joseph’s Healthcare & Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [34 citations]

The following is the list of published articles that have cited the current article.

  • Parameswaran Nair, Angira Dasgupta, Christopher E. Brightling, Kian Fan Chung, Parameswaran Nair, Angira Dasgupta, Christopher E. Brightling, and Kian Fan Chung, “How to Diagnose and Phenotype Asthma,” Clinics In Chest Medicine, vol. 33, no. 3, pp. 445–+, 2012. View at Publisher · View at Google Scholar
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  • Parameswaran Nair, “What is an “eosinophilic phenotype” of asthma?,” Journal of Allergy and Clinical Immunology, vol. 132, no. 1, pp. 81–83, 2013. View at Publisher · View at Google Scholar
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  • Angira Dasgupta, Helen Neighbour, Parameswaran Nair, Angira Dasgupta, Helen Neighbour, and Parameswaran Nair, “Targeted therapy of bronchitis in obstructive airway diseases,” Pharmacology & Therapeutics, vol. 140, no. 3, pp. 213–222, 2013. View at Publisher · View at Google Scholar
  • E. Simms, M. Kjarsgaard, S. Denis, F. E. Hargreave, P. Nair, and M. Larché, “Cytokine responses of peripheral blood mononuclear cells to allergen do not identify asthma or asthma phenotypes,” Clinical & Experimental Allergy, vol. 43, no. 11, pp. 1226–1235, 2013. View at Publisher · View at Google Scholar
  • Erwin W. Gelfand, David B. Jacoby, Benjamin P. Davis, Marc E. Rothenberg, Paneez Khoury, Amy D. Klion, Ramin Lotfi, Neal Spada, Michael Thomas Lotze, Robert P. Schleimer, Atsushi Kato, Dagmar Simon, Robert Kern, Mark C. Lavigne, Michael J. Eppihimer, Florence Roufosse, Annick Massart, Fleur Samantha Benghiat, Philippe Lemaitre, Alain Le Moine, Martin Krahn, Marc Bartoli, Hans-Uwe Simon, Nicolas Levy, Alex Thomas, William W. Busse, Parameswaran Nair, Gail M. Gauvreau, Judah A. Denburg, and Elizabeth R. Bivins-Smithpp. 431–536, 2013. View at Publisher · View at Google Scholar
  • Parameswaran Nair, “Update on clinical inflammometry for the management of airway diseases,” Canadian Respiratory Journal, vol. 20, no. 2, pp. 117–120, 2013. View at Publisher · View at Google Scholar
  • Shyamali C. Dharmage, Vanessa M. McDonald, Michael J. Abramson, Jennifer L. Perret, and Christine F. McDonald, “Distinguishing adult-onset asthma from COPD: A review and a new approach,” International Journal of COPD, vol. 9, pp. 945–962, 2014. View at Publisher · View at Google Scholar
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  • John V. Fahy, “Type 2 inflammation in asthma — present in most, absent in many,” Nature Reviews Immunology, vol. 15, no. 1, pp. 57–65, 2014. View at Publisher · View at Google Scholar
  • Rossana Rossi, Antonella De Palma, Louise Benazzi, Anna Maria Riccio, Giorgio Walter Canonica, and Pierluigi Mauri, “Biomarker discovery in asthma and COPD by proteomic approaches,” PROTEOMICS - Clinical Applications, vol. 8, no. 11-12, pp. 901–915, 2014. View at Publisher · View at Google Scholar
  • Parameswaran Nair, Qiang Zhang, and John D. Brennan, “A perspective on point-of-care tests to detect eosinophilic bronchitis,” Journal of Asthma, vol. 52, no. 3, pp. 254–261, 2014. View at Publisher · View at Google Scholar
  • P. G. Gibson, and V. M. McDonald, “Asthma-COPD overlap 2015: now we are six,” Thorax, vol. 70, no. 7, pp. 683–691, 2015. View at Publisher · View at Google Scholar
  • Nguyen Van Tho, Hye Yun Park, and Yasutaka Nakano, “Asthma-COPD overlap syndrome (ACOS): A diagnostic challenge,” Respirology, vol. 21, no. 3, pp. 410–418, 2015. View at Publisher · View at Google Scholar
  • Parameswaran Nair, Afia Aziz-Ur-Rehman, and Katherine Radford, “Therapeutic implications of ‘neutrophilic asthma’,” Current Opinion in Pulmonary Medicine, vol. 21, no. 1, pp. 33–38, 2015. View at Publisher · View at Google Scholar
  • Parameswaran Nair, and Paul M. O’Byrne, “Measuring Eosinophils to Make Treatment Decisions in Asthma,” Chest, vol. 150, no. 3, pp. 485–487, 2016. View at Publisher · View at Google Scholar
  • Fernando Aleman, Hui Fang Lim, and Parameswaran Nair, “Eosinophilic Endotype of Asthma,” Immunology and Allergy Clinics of North America, vol. 36, no. 3, pp. 559–568, 2016. View at Publisher · View at Google Scholar
  • Balázs Odler, and Veronika Müller, “Asthma-COPD overlap syndrome,” Orvosi Hetilap, vol. 157, no. 33, pp. 1304–1313, 2016. View at Publisher · View at Google Scholar
  • Lalita Fernandes, and Anthony Menezes Mesquita, “The success and safety profile of sputum induction in patients with chronic obstructive pulmonary disease: An Indian experience,” Indian Journal of Tuberculosis, 2016. View at Publisher · View at Google Scholar
  • Hoang Kim Tu Trinh, Ga-Young Ban, Ji-Ho Lee, and Hae-Sim Park, “Leukotriene Receptor Antagonists for the Treatment of Asthma in Elderly Patients,” Drugs & Aging, 2016. View at Publisher · View at Google Scholar
  • Sarah Svenningsen, and Parameswaran Nair, “Asthma Endotypes and an Overview of Targeted Therapy for Asthma,” Frontiers in Medicine, vol. 4, 2017. View at Publisher · View at Google Scholar
  • Kiho Son, Manali Mukherjee, Brendan A.S. McIntyre, Jose C. Eguez, Katherine Radford, Nicola LaVigne, Caroline Ethier, Francis Davoine, Luke Janssen, Paige Lacy, and Parameswaran Nair, “Improved recovery of functionally active eosinophils and neutrophils using novel immunomagnetic technology,” Journal of Immunological Methods, 2017. View at Publisher · View at Google Scholar
  • Terence Ho, Angira Dasgupta, Frederick E. Hargreave, and Parameswaran Nair, “The use of cellular and molecular biomarkers to manage COPD exacerbations,” Expert Review of Respiratory Medicine, pp. 1–9, 2017. View at Publisher · View at Google Scholar
  • Angira Dasgupta, Melanie Kjarsgaard, Dante Capaldi, Fernando Aleman, Leonard C. Altman, Grace Parraga, Paul M. O’Byrne, Parameswaran Nair, Katherine Radford, Colm Boylan, and Thomas N. Wight, “A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis,” European Respiratory Journal, vol. 49, no. 3, 2017. View at Publisher · View at Google Scholar
  • Andriana I. Papaioannou, Konstantinos Kostikas, Anastasia Papaporfyriou, Leonidas Angelakis, Evgenia Papathanasiou, Georgios Hillas, Argyro Mazioti, Petros Bakakos, Nikolaos Koulouris, Spyros Papiris, and Stelios Loukides, “Emphysematous Phenotype is Characterized by Low Blood Eosinophils: A Cross-Sectional Study,” COPD: Journal of Chronic Obstructive Pulmonary Disease, pp. 1–6, 2017. View at Publisher · View at Google Scholar
  • Peter Gibson, Alyssa J Lochrin, Katherine J Baines, Kavita Pabreja, Lisa Wood, and Jodie L Simpson, “Sputum colour can identify patients with neutrophilic inflammation in asthma,” BMJ Open Respiratory Research, vol. 4, no. 1, 2017. View at Publisher · View at Google Scholar
  • Manali Mukherjee, Sarah Svenningsen, and Parameswaran Nair, “Glucocortiosteroid subsensitivity and asthma severity,” Current Opinion in Pulmonary Medicine, vol. 23, no. 1, pp. 78–88, 2017. View at Publisher · View at Google Scholar
  • Anurag Bhalla, Manali Mukherjee, and Parameswaran Nair, “Airway Eosinophilopoietic and Autoimmune Mechanisms of Eosinophilia in Severe Asthma,” Immunology and Allergy Clinics of North America, 2018. View at Publisher · View at Google Scholar
  • Sarah Svenningsen, Rachel L. Eddy, Hui Fang Lim, P. Gerard Cox, Parameswaran Nair, and Grace Parraga, “Sputum Eosinophilia and Magnetic Resonance Imaging Ventilation Heterogeneity in Severe Asthma,” American Journal of Respiratory and Critical Care Medicine, vol. 197, no. 7, pp. 876–884, 2018. View at Publisher · View at Google Scholar
  • Manali Mukherjee, and Parameswaran Nair, “Autoimmune Responses in Severe Asthma,” Allergy, Asthma & Immunology Research, vol. 10, no. 5, pp. 428, 2018. View at Publisher · View at Google Scholar